TISSUES

Tissue expression database

CAVIN4 tissues

CAVIN4 [ENSP00000418668]

Caveolae-associated protein 4; Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation. Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and regulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes through MAPK1/3 activation. Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes (By similarity). Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway ; Belongs to the CAVIN family.

Synonyms:  CAVIN4,  CAVIN4p,  hCAVIN4,  Q5BKX8,  Q5BKX8p ...

Linkouts:  STRING  Pharos  UniProt

0 1 2 3 4 5 Confidence