TISSUES

Tissue expression database

ABHD4 tissues

ABHD4 [ENSP00000414558]

(Lyso)-N-acylphosphatidylethanolamine lipase; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N- acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine. ; Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.

Synonyms:  ABHD4,  ABHD4p,  hABHD4,  F5GZC9,  F5H067 ...

Linkouts:  STRING  Pharos  UniProt

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