TISSUES

Tissue expression database

SLC4A8 tissues

SLC4A8 [ENSP00000405812]

Electroneutral sodium bicarbonate exchanger 1; Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.

Synonyms:  SLC4A8,  SLC4A8p,  hSLC4A8,  Q2Y0W8,  Q2Y0W8p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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