NOTUM tissues
NOTUM [ENSP00000387310]
Palmitoleoyl-protein carboxylesterase NOTUM; Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors .
Synonyms: NOTUM, C9JYG8, K7EIG3, Q6P988, C9JYG8p ...