GPSM2 tissues
GPSM2 [ENSP00000385510]
G-protein-signaling modulator 2; Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:11781568, PubMed:15632202, PubMed:21816348). Required for cortical dynein-dynactin complex recruitment during metaphase . Plays a role in metaphase spindle orientation . Plays also an important role in asymmetric cell divisions . Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (By similarity). ECO:0000269|PubMed:11781568, ECO:0000269|PubMed:15632202,
Synonyms: GPSM2, GPSM2p, hGPSM2, A0A024R0F8, A0A2R8Y673 ...