TISSUES

Tissue expression database

MAPK4 tissues

MAPK4 [ENSP00000383234]

Mitogen-activated protein kinase 4; Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

Synonyms:  MAPK4,  MAPK4p,  hMAPK4,  B4DEW2,  K7ELV1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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