TISSUES

Tissue expression database

MYBBP1A tissues

MYBBP1A [ENSP00000370968]

Myb-binding protein 1A; May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity). Has a role in rRNA biogenesis together with PWP1 . ; Belongs to the MYBBP1A family.

Synonyms:  MYBBP1A,  MYBBP1Ap,  hMYBBP1A,  I3L1L3,  I3L2H8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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