TISSUES

Tissue expression database

PLA2G2F tissues

PLA2G2F [ENSP00000364243]

Group IIF secretory phospholipase A2; May play a role in lipid mediator production in inflammatory conditions, by providing arachidonic acid to downstream cyclooxygenases and lipoxygenases (By similarity). Phospholipase A2, which catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn- phosphoglycerides . Hydrolyzes phosphatidylethanolamine more efficiently than phosphatidylcholine, with only a modest preference for arachidonic acid versus linoelic acid at the sn-2 position. Comparable activity toward 1-palmitoyl-2-oleoyl- phosphatidylserine vesicles to that toward 1-palmitoyl-2-oleoyl- phosphatidylglycerol (By similarity). Hydrolyzes phosphatidylglycerol versus phosphatidylcholine with a 15-fold preference .

Synonyms:  PLA2G2F,  PLA2G2Fp,  hPLA2G2F,  Q9BZM2,  Q9BZM2p ...

Linkouts:  STRING  Pharos  UniProt

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