TISSUES

Tissue expression database

EDEM2 tissues

EDEM2 [ENSP00000363616]

ER degradation-enhancing alpha-mannosidase-like protein 2; Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner . May initiate ERAD by promoting the first mannose trimming step of ERAD substrates, from Man9GlcNAc2 to Man8GlcNAc2 . Seems to recognize and bind to exposed hydrophobic regions in target proteins (By similarity).

Synonyms:  EDEM2,  EDEM2p,  hEDEM2,  MMP24-AS1-EDEM2,  Q9BV94 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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