TISSUES

Tissue expression database

RAB39B tissues

RAB39B [ENSP00000358466]

Ras-related protein Rab-39B; Small GTPases Rab involved in autophagy . The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion . May regulate the homeostasis of SNCA/alpha-synuclein. Together with PICK1 proposed to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR compostion at the post- synapses and thus synaptic transmission (By similarity).

Synonyms:  RAB39B,  RAB39Bp,  hRAB39B,  Q96DA2,  Q96DA2p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

0 1 2 3 4 5 Confidence