TISSUES

Tissue expression database

JensenLab

IGSF8 tissues

IGSF8 [ENSP00000357065]

Immunoglobulin superfamily member 8; May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. ECO:0000269|PubMed:12750295, ECO:0000269|PubMed:12752121,

Synonyms:  IGSF8,  IGSF8p,  hIGSF8,  C9J8Z4,  Q969P0 ...

Linkouts:  STRING  Pharos  UniProt

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