TISSUES

Tissue expression database

PEA15 tissues

PEA15 [ENSP00000357055]

Astrocytic phosphoprotein PEA-15; Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.

Synonyms:  PEA15,  PEA15p,  hPEA15,  B1AKZ4,  B1AKZ5 ...

Linkouts:  STRING  Pharos  UniProt

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