TRIM58 tissues
TRIM58 [ENSP00000355437]
E3 ubiquitin-protein ligase TRIM58; E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.
Synonyms: TRIM58, TRIM58p, hTRIM58, Q8NG06, Q8NG06p ...