TISSUES

Tissue expression database

PLXNA4 tissues

PLXNA4 [ENSP00000352882]

Plexin-A4; Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).

Synonyms:  PLXNA4,  PLXNA4p,  hPLXNA4,  A0A024R7A6,  PLXNA4B ...

Linkouts:  STRING  Pharos  UniProt

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