TISSUES

Tissue expression database

QPCT tissues

QPCT [ENSP00000344829]

Glutaminyl-peptide cyclotransferase; Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N- terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.

Synonyms:  QPCT,  A0A3B3IUD5,  B5MCZ9,  C9JS14,  Q16769 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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