TISSUES

Tissue expression database

RBPMS tissues

RBPMS [ENSP00000340176]

RNA-binding protein with multiple splicing; Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins . Binds to poly(A) RNA .

Synonyms:  RBPMS,  B4E3T4,  E5RFP4,  E5RJ31,  E5RJD7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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