TISSUES

Tissue expression database

ZMIZ1 tissues

ZMIZ1 [ENSP00000334474]

Zinc finger MIZ domain-containing protein 1; Acts as transcriptional coactivator. Increases ligand- dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation . Also functions as a transcriptional coactivator in the TGF-beta signaling pathway by increasing the activity of the SMAD3/SMAD4 transcriptional complex . Involved in transcriptional activation of a subset of NOTCH1 target genes including MYC. Involved in thymocyte and T cell development (By similarity). ECO:0000269|PubMed:14609956, ECO:0000269|PubMed:16777850,

Synonyms:  ZMIZ1,  ZMIZ1p,  hZMIZ1,  A0A087WYE6,  F6WR09 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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