TISSUES

Tissue expression database

CMTM4 tissues

CMTM4 [ENSP00000333833]

CKLF-like MARVEL transmembrane domain-containing protein 4; Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD- L1/CD274 from being polyubiquitinated and targeted for degradation. ; Belongs to the chemokine-like factor family.

Synonyms:  CMTM4,  CMTM4p,  hCMTM4,  J3QRP2,  Q8IZR5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

0 1 2 3 4 5 Confidence