TISSUES

Tissue expression database

WDFY4 tissues

WDFY4 [ENSP00000320563]

WD repeat- and FYVE domain-containing protein 4; Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.

Synonyms:  WDFY4,  WDFY4p,  hWDFY4,  A0A1W2PQ91,  Q6ZS81 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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