TISSUES

Tissue expression database

NSUN3 tissues

NSUN3 [ENSP00000318986]

tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial; Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt- tRNA(Met) . mt- tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5- formylcytosine (f(5)c) at this position (PubMed:27497299, PubMed:27214402, PubMed:27356879). mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation . ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

Synonyms:  NSUN3,  NSUN3p,  hNSUN3,  F8WF52,  Q9H649 ...

Linkouts:  STRING  Pharos  UniProt

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