TISSUES

Tissue expression database

RFNG tissues

RFNG [ENSP00000307971]

Beta-1,3-N-acetylglucosaminyltransferase radical fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in enhancement of NOTCH1 activation by DLL1 and JAG1. May be involved in limb formation and in neurogenesis.

Synonyms:  RFNG,  F5H3H7,  J3QLN0,  Q9Y644,  F5H3H7p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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