TISSUES

Tissue expression database

MUS81 tissues

MUS81 [ENSP00000307853]

Crossover junction endonuclease MUS81; Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. ECO:0000269|PubMed:12374758, ECO:0000269|PubMed:12686547, ECO:0000269|PubMed:12721304, ECO:0000269|PubMed:14617801, ECO:0000269|PubMed:15805243, ECO:0000269|PubMed:17289582,; Belongs to the XPF family.

Synonyms:  MUS81,  MUS81p,  hMUS81,  E9PII7,  E9PL60 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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