E4F1 tissues
E4F1 [ENSP00000301727]
Transcription factor E4F1; May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin- associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription.
Synonyms: E4F1, E4F1p, hE4F1, H3BN24, H3BQZ4 ...