TISSUES

Tissue expression database

CAPN2 tissues

CAPN2 [ENSP00000295006]

Calpain-2 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' . Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).

Synonyms:  CAPN2,  CAPN2p,  hCAPN2,  C9JWY7,  P17655 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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