TISSUES

Tissue expression database

SASS6 tissues

SASS6 [ENSP00000287482]

Spindle assembly abnormal protein 6 homolog; Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers. Required for the recruitment of STIL to the procentriole and for STIL-mediated centriole amplification . ECO:0000269|PubMed:16244668, ECO:0000269|PubMed:17681131,

Synonyms:  SASS6,  SASS6p,  hSASS6,  Q6UVJ0,  Q6UVJ0p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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