TISSUES

Tissue expression database

HAT1 tissues

HAT1 [ENSP00000264108]

Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage. ECO:0000269|PubMed:20953179, ECO:0000269|PubMed:22615379,; Belongs to the HAT1 family.

Synonyms:  HAT1,  HAT1p,  hHAT1,  F8W9G7,  F8WEW1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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