TISSUES

Tissue expression database

E2F3 tissues

E2F3 [ENSP00000262904]

Transcription factor E2F3; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity).

Synonyms:  E2F3,  E2F3p,  hE2F3,  A0A087X0B6,  O00716 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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