TISSUES

Tissue expression database

APH1B tissues

APH1B [ENSP00000261879]

Gamma-secretase subunit APH-1B; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (amyloid-beta precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A; Belongs to the APH-1 family.

Synonyms:  APH1B,  APH1Bp,  hAPH1B,  H0YKZ9,  H0YLT0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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