TISSUES

Tissue expression database

TAF5L tissues

TAF5L [ENSP00000258281]

TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable). With TAF6L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state (By similarity). ; Belongs to the WD repeat TAF5 family.

Synonyms:  TAF5L,  TAF5Lp,  hTAF5L,  O75529,  Q5TDI7 ...

Linkouts:  STRING  Pharos  UniProt

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