TISSUES

Tissue expression database

DVL2 tissues

DVL2 [ENSP00000005340]

Segment polarity protein dishevelled homolog DVL-2; Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling; Belongs to the DSH family.

Synonyms:  DVL2,  DVL2p,  hDVL2,  I3L0M7,  I3L0Z8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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