TRMT112 tissues
TRMT112 [ENSP00000438349]
Multifunctional methyltransferase subunit TRM112-like protein; Acts as an activator of both rRNA/tRNA and protein methyltransferases . Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA . The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor . The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species . Involved in the pre-rRNA processing steps leading to small-subunit rRNA production .
Synonyms: TRMT112, TRMT112p, hTRMT112, A0A024R565, F5GX77 ...