TISSUES

Tissue expression database

API5 tissues

API5 [ENSP00000431391]

Apoptosis inhibitor 5; Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs; Belongs to the API5 family.

Synonyms:  API5,  API5p,  hAPI5,  E9PQK6,  G3V1C3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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