TISSUES

Tissue expression database

ATG12 tissues

ATG12 [ENSP00000425107]

Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. ECO:0000269|PubMed:19074260, ECO:0000269|PubMed:19164948,

Synonyms:  ATG12,  ATG12p,  hATG12,  D6RB14,  H0Y9W4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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