TISSUES

Tissue expression database

NSFL1C tissues

NSFL1C [ENSP00000418529]

NSFL1 cofactor p47; Reduces the ATPase activity of VCP (By similarity). Necessary for the fragmentation of Golgi stacks during mitosis and for VCP- mediated reassembly of Golgi stacks after mitosis (By similarity). May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity). Inhibits the activity of CTSL (in vitro) . Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase . Also, regulates spindle orientation during mitosis ; Belongs to the NSFL1C family.

Synonyms:  NSFL1C,  NSFL1Cp,  hNSFL1C,  F2Z2K0,  G3V4V8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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