NSFL1C tissues
NSFL1C [ENSP00000418529]
NSFL1 cofactor p47; Reduces the ATPase activity of VCP (By similarity). Necessary for the fragmentation of Golgi stacks during mitosis and for VCP- mediated reassembly of Golgi stacks after mitosis (By similarity). May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity). Inhibits the activity of CTSL (in vitro) . Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase . Also, regulates spindle orientation during mitosis ; Belongs to the NSFL1C family.
Synonyms: NSFL1C, NSFL1Cp, hNSFL1C, F2Z2K0, G3V4V8 ...