UNC5D tissues
UNC5D [ENSP00000385143]
Netrin receptor UNC5D; Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). May play a role in apoptosis in response to DNA damage . It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand . Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity). ; Belongs to the unc-5 family.
Synonyms: UNC5D, UNC5Dp, hUNC5D, C9J1I0, C9J2B6 ...