TISSUES

Tissue expression database

APIP tissues

APIP [ENSP00000379133]

Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death. ECO:0000269|PubMed:15262985, ECO:0000269|PubMed:22837397,; Belongs to the aldolase class II family. MtnB subfamily.

Synonyms:  APIP,  Q96GX9,  S4R3D6,  Q96GX9p,  hQ96GX9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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