TISSUES

Tissue expression database

KLHL21 tissues

KLHL21 [ENSP00000366886]

Kelch-like protein 21; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

Synonyms:  KLHL21,  KLHL21p,  hKLHL21,  K7ELI0,  K7EMF2 ...

Linkouts:  STRING  Pharos  UniProt

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