TISSUES

Tissue expression database

SVBP tissues

SVBP [ENSP00000361599]

Small vasohibin-binding protein; Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin (PubMed:29146869, PubMed:31270470, PubMed:31235911, PubMed:31324789, PubMed:31171830, PubMed:31235910). This activity is critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning . Also required to enhance the solubility and secretion of VASH1 and VASH2 . Plays a role in axon and excitatory synapse formation . ECO:0000269|PubMed:29146869, ECO:0000269|PubMed:30607023, ECO:0000269|PubMed:31171830, ECO:0000269|PubMed:31235910, ECO:0000269|PubMed:31235911, ECO:0000269|PubMed:31270470,; Belongs to the SVBP family.

Synonyms:  SVBP,  Q8N300,  Q8N300p,  hQ8N300,  374969 ...

Linkouts:  STRING  Pharos  UniProt

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