TISSUES

Tissue expression database

AGBL4 tissues

AGBL4 [ENSP00000360905]

Cytosolic carboxypeptidase 6; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.

Synonyms:  AGBL4,  AGBL4p,  hAGBL4,  B1AMW3,  B1ANV5 ...

Linkouts:  STRING  Pharos  UniProt

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