TISSUES

Tissue expression database

AFG1L tissues

AFG1L [ENSP00000357973]

AFG1-like ATPase; Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain . Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress .

Synonyms:  AFG1L,  AFG1Lp,  hAFG1L,  A6ZJA2,  H0Y5F4 ...

Linkouts:  STRING  Pharos  UniProt

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