TISSUES

Tissue expression database

NENF tissues

NENF [ENSP00000355955]

Neudesin; Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival . Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes (By similarity). Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways (By similarity). Neurotrophic activity is enhanced by binding to heme (By similarity). Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity).

Synonyms:  NENF,  Q9UMX5,  Q9UMX5p,  hQ9UMX5,  29937 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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