TISSUES

Tissue expression database

GFRAL tissues

GFRAL [ENSP00000343636]

GDNF family receptor alpha-like; Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. ; Belongs to the GDNFR family.

Synonyms:  GFRAL,  Q6UXV0,  Q6UXV0p,  hQ6UXV0,  389400 ...

Linkouts:  STRING  Pharos  UniProt

0 1 2 3 4 5 Confidence