RRP1B tissues
RRP1B [ENSP00000339145]
Ribosomal RNA processing protein 1 homolog B; Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1 . Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus . Involved in regulation of mRNA splicing (By similarity). Inhibits SIPA1 GTPase activity (By similarity). Involved in regulating expression of extracellular matrix genes (By similarity). Associates with chromatin and may play a role in modulating chromatin structure . ECO:0000269|PubMed:19710015, ECO:0000269|PubMed:20040599,
Synonyms: RRP1B, RRP1Bp, hRRP1B, Q14684, Q14684p ...