TISSUES

Tissue expression database

ZGPAT tissues

ZGPAT [ENSP00000332013]

Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.

Synonyms:  ZGPAT,  A0A0S2Z5X3,  Q8N5A5,  X6RGY1,  Q8N5A5p ...

Linkouts:  STRING  Pharos  UniProt

0 1 2 3 4 5 Confidence