TSPYL5 tissues
TSPYL5 [ENSP00000322802]
Testis-specific Y-encoded-like protein 5; Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.
Synonyms: TSPYL5, TSPYL5p, hTSPYL5, Q86VY4, Q86VY4p ...