CHAF1B tissues
CHAF1B [ENSP00000315700]
Chromatin assembly factor 1 subunit B; Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. ; Belongs to the WD repeat HIR1 family.
Synonyms: CHAF1B, CHAF1Bp, hCHAF1B, Q13112, Q13112p ...