TISSUES

Tissue expression database

GGA2 tissues

GGA2 [ENSP00000311962]

ADP-ribosylation factor-binding protein GGA2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif . Mediates export of the GPCR receptor ADRA2B to the cell surface . Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans- Golgi network .

Synonyms:  GGA2,  GGA2p,  hGGA2,  H3BMM6,  H3BMN6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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