TISSUES

Tissue expression database

FBXO31 tissues

FBXO31 [ENSP00000310841]

F-box only protein 31; Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor; Belongs to the FBXO31 family.

Synonyms:  FBXO31,  FBXO31p,  hFBXO31,  A0A0C4DGU8,  A0A1B0GV77 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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