EIF4EBP3 tissues
EIF4EBP3 [ENSP00000308472]
Eukaryotic translation initiation factor 4E-binding protein 3; Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.
Synonyms: EIF4EBP3, O60516, O60516p, hO60516, 4E-BP3 ...