TISSUES

Tissue expression database

KREMEN2 tissues

KREMEN2 [ENSP00000304422]

Kremen protein 2; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation.

Synonyms:  KREMEN2,  KREMEN2p,  hKREMEN2,  Q8NCW0,  Q8NCW0p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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